The Agilent 1260 Infinity is a modular High-Performance Liquid Chromatography (HPLC) and UHPLC system designed for routine analytical work, method development, and quality control. Succeeding the industry-standard 1200 Series, the 1260 Infinity raised the standard HPLC pressure limit to 600 bar, allowing for higher flow rates, narrower columns, and increased resolution without sacrificing backward compatibility for established HPLC methods. As a highly configurable platform, its exact specifications depend on the chosen pump, autosampler, column compartment, and detector modules.
Specifications
System Overview
| Parameter | Value |
|---|---|
| System Type | HPLC / UHPLC |
| Maximum Operating Pressure | 600 bar (8700 psi) |
| Configurable Modules | Pump, Autosampler, Column Compartment, Detector, Fraction Collector (configuration dependent) |
Pump / Solvent Delivery
| Parameter | Value |
|---|---|
| Operating Pressure Range | Up to 600 bar (at 0 to 5 mL/min); Up to 200 bar (at 5 to 10 mL/min) |
Autosampler / Sample Injection
| Parameter | Value |
|---|---|
| Injection Volume Range | 0.1 to 100 µL (standard configuration) |
| Sample Capacity (Vials) | 100 × 2 mL vials (standard tray) |
Column Compartment / Thermostat
| Parameter | Value |
|---|---|
| Temperature Control Range | 10 °C below ambient to 80 °C (standard thermostatted column compartment) |
| Column Capacity (Max Quantity) | Up to 3 columns (up to 30 cm length) |
Software and Communications
| Parameter | Value |
|---|---|
| Controller Area Network (CAN) Support | Yes (inter-module synchronization and control) |
Fluidics
| Parameter | Value |
|---|---|
| Compressibility Compensation | Automatic, continuous |
Safety
| Parameter | Value |
|---|---|
| Leak Detection | Built-in leak sensors in all modules with safe leak handling |
GLP & Diagnostics
| Parameter | Value |
|---|---|
| Early Maintenance Feedback (EMF) | Continuous tracking of instrument usage with user-settable limits and alarm messages |
Performance
| Parameter | Value |
|---|---|
| Gradient Mixing Mechanism | Low-pressure mixing (Quaternary pump) / High-pressure mixing (Binary pump) |
Compliance & GLP
| Parameter | Value |
|---|---|
| Component Tracking (RFID) | RFID tags for automatic recognition of columns, UV lamps, and flow cells (module dependent) |
Technology
Liquid Chromatography (HPLC / UHPLC)
Applications
Analytical chemistry, pharmaceutical QA/QC, environmental testing, food and beverage analysis, and biochemical research