Prominence

ShimadzuLiquid

Shimadzu Prominence is a modular high‑performance liquid chromatography (HPLC) platform. It supports isocratic and gradient configurations using a wide range of compatible pumps, autosamplers, column ovens, degassers, and detectors under centralized LAN control.

Specifications

General

ParameterValue
InterfacesEthernet (via CBM‑20A/CBM‑20A Lite system controller); module instrument bus; front‑panel I/O (module‑dependent)
DisplayFront‑panel LCD/keypad on modules; browser‑based interface via CBM‑20A

Physical

ParameterValue
Power Supply100–240 V AC, 50/60 Hz (per module; consumption is module‑dependent)

System Performance

ParameterValue
System architectureModular, stackable HPLC system with centralized controller
Maximum operating pressureUp to 40 MPa (pump‑dependent)
Gradient types supportedIsocratic, binary HPG, ternary/quaternary LPG (configuration‑dependent)
Mixing modesHigh‑pressure and low‑pressure mixing (configuration‑dependent)
DegassingVacuum membrane degassing available (module‑dependent)

Solvent Delivery – Pumps

ParameterValue
Pumps (compatible)LC‑20AD, LC‑20AT (analytical class)
Prime/purge capabilityAvailable on solvent delivery modules (module‑dependent)

Gradient Formation and Mixing

ParameterValue
Gradient formationHPG using dual pumps; LPG using multi‑solvent proportioning (configuration‑dependent)
Quaternary solvent selectionSupported via low‑pressure proportioning (configuration‑dependent)

Degasser

ParameterValue
Degasser modelsDGU‑20A3 (3‑channel), DGU‑20A5 (5‑channel)

Autosampler / Sample Manager

ParameterValue
Autosampler modelsSIL‑20A; SIL‑20AC (with Peltier cooling)
Autosampler coolingPeltier cooling with SIL‑20AC

Column Oven / Thermostat

ParameterValue
Column oven modelsCTO‑20A series

Detector – UV‑Vis Absorbance

ParameterValue
UV‑Vis detector optionsSPD‑20A / SPD‑20AV series (variable‑wavelength)

Detector – Photodiode Array (PDA/DAD)

ParameterValue
PDA detector optionSPD‑M20A photodiode array detector

Detector – Fluorescence (FLD)

ParameterValue
Fluorescence detector optionRF‑20Axs series

Detector – Refractive Index (RID)

ParameterValue
Refractive index detector optionAvailable (model‑dependent)

Connectivity and Interfaces

ParameterValue
System controllerCBM‑20A or CBM‑20A Lite
LAN control/monitoringEthernet‑based system control; browser monitoring via CBM‑20A

Software and Data Management

ParameterValue
Software compatibilityShimadzu LCsolution / LabSolutions (version‑dependent)
21 CFR Part 11Supported via Shimadzu compliance software options (software‑dependent)
Remote system configurationCentralized method/sequence control via controller software

Physical Specifications

ParameterValue
Stacking footprintModular stack arrangement (module dimensions vary by unit)

Safety Features

ParameterValue
Leak managementInternal leak sensing in modules (module‑dependent)

Valves and Switching Modules

ParameterValue
Valve/switching optionsHigh‑pressure and low‑pressure valve modules available

Mass Spectrometer Interface

ParameterValue
MS interfacingConfigurable via appropriate interfaces/sources (system‑dependent)

Materials and Wetted Parts

ParameterValue
Materials in flow pathStainless steel and polymer components (module‑dependent)

Documentation

ParameterValue
DocumentationUser manuals, installation guides, and IQ/OQ/PQ documentation available

Power Requirements

ParameterValue
Regional power optionsUniversal‑input modules for global mains (module‑dependent)